The Phase trial was randomized, double-blind, placebo-controlled trial evaluating ganaxolone as add-on therapy for adults with partial onset gaba gaba clothers seizures, who continued to have seizures even while taking up to three antiepileptic drugs AED. 39 Adjustable Fluidic Lenses for Eyesight Correction Applications Physics Genaral Physics Feb 24, 2009. Direct evidence of ethanol augmentation of GABAA receptor function, measured either by electrophysiological techniques or agonist-mediated Cl flux, has been reported 3,15. Current medical belief is that GABA will not pass the blood brain barrier. These drugs include but are not limited to barbiturates, benzodiazepines, and alcohol. All patients completing the double blind portion were eligible to enter an open label extension trial, with 95 percent of patients electing to continue therapy.